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Brief Report
Novel Peptide Identified
Procrastinatin reaction catalyzed by inafukindase
PHILADELPHIA, PA--Researchers at the University
of Pennsylvania have identified a physiologically active peptide that
is thought to play a pivotal role in the initiation and sustaining of
goal-oriented behavior in animals and humans.
In a paper presented by Carlene Bolenbaugh, Ph.D.
last week at the Lamere Institute For Biotechnology, the characteristics
and pharmacokinetics of the peptide, dubbed “procrastinatin,” were
outlined:
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Figure 1: Side chains (1,2) being cleaved from
pre-procrastinatin (P) by the enzyme inafukindase (IFD) to form
procrastinatin, a peptide strongly associated with what you got
done today. The yellow oval is labeled “beta”, which
is like Greek for “b”. Pac Man appears at lower right.
Click
for Powerpoint slide
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“An elevated serum level of procrastinatin
correlates quite remarkably with a basic inability to get things done,” said
Bolenbaugh. “Basically, the higher your level is, the longer it’ll
take you to get around to doing what you should probably have been doing
last month and the month before.”
“For example, take the fact that this paper
took me more than six years to write. See, I can explain that: Due to
near-toxic levels of inafukindase, I spent most of the last decade
in a procrastinatin
coma.”
Scientists are now being urged to develop inhibitor
molecules to counteract the neurological effects of procrastinatin and
inafukindase.
“Yeah, I’ll get right on that,” says Bolenbaugh. “Soon.
Real soon.”
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