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Heart Transplantion Study
Halted Abruptly
Transplant of placebo "a disaster," admit
researchers
BOSTON, MA - Researchers at Boston's Holy Cross Medical
Center have abruptly terminated a prospective study of heart transplantation
outcomes, said a spokesperson for the group Thursday.
The study, which had originally been projected to
last ten to twelve years, was canceled after only three months after the
control population, which received transplantation of a heart-shaped styrofoam
placebo in lieu of a real heart, was found to have unexpectedly excessive
morbidity and mortality, nearing 100% in some cases.
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Mark O' Reilly, MD supervises
placebo transplantion
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"Basically, we've proven a couple of things,"
said Mark O' Reilly, MD, a cardiothoracic surgeon. "First and foremost,
heart transplantation saves lives. Secondly, placebo transplantation does
exactly the opposite of that. [It's] quite a disaster."
As compared with patients receiving an actual heart,
patients receiving a placebo were reported to experience a higher incidence
of hypotension, shock, and fulminant hemodynamic embarrassment. Resuscitative
efforts were generally futile.
"We were obviously hoping we'd have better results
with the placebo heart," said O' Reilly.
Of note, one placebo recipient, Barney Ross of Pismo
Beach, CA, has continued to do well with his styrofoam heart more than
45 days after receiving it. Although unable to participate in most athletic
activities, he plays golf three times a week, and maintains an otherwise
normal lifestyle.
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